Moving right along in this season, the CFB picks for 2025 Week 6 are here. As always, we find 10 games, and we pick them.

This has been a difficult and weird season for Bracket Yard. Picking the winners of the games outright has not been so difficult, but against the spread? That’s been the challenge. Some teams are not doing what we thought they would do, that’s for sure. Others have coughed up backdoor covers late in games. Nevertheless, it’s all just fun and games.

Out of the 51 games, the ten we have selected below are picked straight-up and against-the-spread.

Before We Continue

Important: Please remember that any selections herein are for entertainment purposes only. We are not affiliated with any gambling operation or professional team, nor are we encouraging you to do anything with these opinions. Please consult Bracket Yard’s Notice to Visitors for further clarification.

CFB Picks, 2025 Week 6