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2025 NFL Picks: Straight-Up & Spread

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2025 NFL Picks - 2025 football picks - team locations on a black LCD board resembling that of a sportsbook

One of the glories of the return of football season are our selections, and we now bring you the 2025 NFL picks.

Before we go any further: Please remember that any selections herein are for entertainment purposes only, and at that, mostly just to satisfy the curiosity of the editor.  We are not affiliated with any gambling operation or professional team, nor are we encouraging you to do anything with these opinions.  Please consult Bracket Yard’s Notice to Visitors for further clarification.

Over the course of the 2025 season, we have decided to pick every game, starting with Week 1.  Our focus will be the straight-up picks as well as against-the-spread picks.  No over-under this year, but you all can figure that out for yourselves.

2025 NFL Picks: Week-by-Week

The most recent week picked will appear at the top.

Week 14

Game (Fav.)Date/Time (ET)S/U PickATS Pick
DAL @ DET (-3)Thu 8:15pmDetroitDET -3
SEA (-7) @ ATLSun 1:00pmSeattleSEA -7
CIN @ BUF (-5.5)Sun 1:00pmBuffaloBUF -5.5
TEN @ CLE (-4.5)Sun 1:00pmClevelandCLE -4.5
WSH @ MIN (-1.5)Sun 1:00pmMinnesotaMIN -1.5
MIA (-2.5) @ NYJSun 1:00pmNew YorkNYJ +2.5
NO @ TB (-8.5)Sun 1:00pmTampa BayTB -8.5
IND (-1.5) @ JAXSun 1:00pmJacksonvilleJAX +1.5
PIT @ BAL (-6)Sun 1:00pmBaltimorePIT +6
DEN (-7.5) @ LVSun 4:05pmDenverDEN -7.5
CHI @ GB (-6.5)Sun 4:25pmGreen BayCHI +6.5
LAR (-7.5) @ ARISun 4:25pmLos AngelesLAR -7.5
HOU @ KC (-3.5)Sun 8:20pmKansas CityKC -3.5
PHI (-3) @ LACMon 8:15pmLos AngelesLAC +3

Week 13

Game (Fav.)Date/Time (ET)S/U PickATS Pick
GB @ DET (-2.5)Thu 1:00pmDetroitDET -2.5
KC (-3) @ DALThu 4:30pmDallasDAL +3
CIN @ BAL (-7)Thu 8:20pmBaltimoreBAL -7
CHI @ PHI (-7)Fri 3:00pmPhiladelphiaPHI +7
SF (-5.5) @ CLESun 1:00pmSan FranciscoSF -5.5
JAX (-6.5) @ TENSun 1:00pmJacksonvilleJAX -6.5
HOU @ IND (-4.5)Sun 1:00pmHoustonHOU +4.5
NO @ MIA (-6)Sun 1:00pmMiamiMIA -6
ATL (-2.5) @ NYJSun 1:00pmAtlantaATL -2.5
ARI @ TB (-3)Sun 1:00pmTampa BayTB -3
LAR (-10.5) @ CARSun 1:00pmLos AngelesCAR +10.5
MIN @ SEA (-10.5)Sun 4:05pmSeattleSEA -10.5
BUF (-3.5) @ PITSun 4:25pmBuffaloBUF -3.5
LV @ LAC (-9.5)Sun 4:25pmLos AngelesLAC -9.5
DEN (-6.5) @ WSHSun 8:20pmDenverDEN -6.5
NYG @ NE (-7.5)Mon 8:15pmNew EnglandNE -7.5

Week 12

Game (Fav.)Date/Time (ET)S/U PickATS Pick
BUF (-6) @ HOUThu 8:15pmBuffaloBUF -6
PIT @ CHI (-2.5)Sun 1:00pmChicagoCHI -2.5
NE (-8) @ CINSun 1:00pmNew EnglandNE -8
NYG @ DET (-10.5)Sun 1:00pmDetroitNYG +10.5
MIN @ GB (-6)Sun 1:00pmGreen BayGB -6
SEA (-13.5) @ TENSun 1:00pmSeattleSEA -13.5
IND @ KC (-3.5)Sun 1:00pmKansas CityKC -3.5
NYJ @ BAL (-13.5)Sun 1:00pmBaltimoreBAL -13.5
CLE @ LV (-4)Sun 4:05pmLas VegasLV -4
JAX (-3) @ ARISun 4:05pmJacksonvilleJAX -3
PHI (-3.5) @ DALSun 4:25pmPhiladelphiaPHI -3.5
ATL @ NO (-1.5)Sun 4:25pmNew OrleansNO -1.5
TB @ LAR (-7)Sun 8:20pmLos AngelesLAR -7
CAR @ SF (-7)Mon 8:15pmSan FranciscoSF -7

Week 11

Game (Fav.)Date/Time (ET)S/U PickATS Pick
NYJ @ NE (-13.5)Thu 8:15pmNew EnglandNE -13.5
WSH @ MIA (-3)Sun 9:30amMiamiMIA -3
CAR @ ATL (-3.5)Sun 1:00pmCarolinaCAR +3.5
TB @ BUF (-5.5)Sun 1:00pmBuffaloBUF -5.5
HOU (-7.5) @ TENSun 1:00pmHoustonHOU -7.5
CHI @ MIN (-3)Sun 1:00pmChicagoCHI +3
GB (-7.5) @ NYGSun 1:00pmGreen BayGB -7.5
CIN @ PIT (-5.5)Sun 1:00pmPittsburghCIN +5.5
LAC (-3) @ JAXSun 1:00pmLos AngelesLAC -3
SEA @ LAR (-3)Sun 4:05pmLos AngelesLAR -3
SF (-2.5) @ ARISun 4:05pmSan FranciscoSF -2.5
BAL (-8.5) @ CLESun 4:25pmBaltimoreBAL -8.5
KC (-4) @ DENSun 4:25pmDenverDEN +4
DET @ PHI (-2.5)Sun 8:20pmDetroitDET +2.5
DAL (-3.5) @ LVMon 8:15pmDallasDAL -3.5

Week 10

Game (Fav.)Date/Time (ET)S/U PickATS Pick
LV @ DEN (-10)Thu 8:15pmDenverDEN -10
ATL @ IND (-6.5)Sun 9:30amIndianapolisIND -6.5
BUF (-10) @ MIASun 1:00pmBuffaloBUF -10
NE @ TB (-2.5)Sun 1:00pmTampa BayTB -2.5
CLE (-2.5) @ NYJSun 1:00pmNew YorkNYJ +2.5
BAL (-4) @ MINSun 1:00pmBaltimoreBAL -4
NYG @ CHI (-4.5)Sun 1:00pmChicagoCHI -4.5
JAX @ HOU (-1)Sun 1:00pmHoustonHOU -1
NO @ CAR (-5.5)Sun 1:00pmCarolinaCAR -5.5
ARI @ SEA (-7)Sun 4:05pmSeattleSEA -7
DET (-8.5) @ WSHSun 4:25pmDetroitDET -8.5
LAR (-4) @ SFSun 4:25pmLos AngelesLAR -4
PIT @ LAC (-3)Sun 8:20pmLos AngelesLAC -3
PHI @ GB (-2.5)Mon 8:15pmPhiladelphiaPHI +2.5

Week 9

Game (Fav.)Date/Time (ET)S/U PickATS Pick
BAL (-7.5) @ MIAThu 8:15pmBaltimoreBAL -7.5
CHI (-2.5) @ CINSun 1:00pmChicagoCHI -2.5
MIN @ DET (-9.5)Sun 1:00pmDetroitDET -9.5
CAR @ GB (-13.5)Sun 1:00pmGreen BayCAR +13.5
LAC (-9.5) @ TENSun 1:00pmLos AngelesLAC -9.5
ATL @ NE (-5.5)Sun 1:00pmNew EnglandNE -5.5
SF (-2.5) @ NYGSun 1:00pmNew YorkNYG +2.5
IND (-3.5) @ PITSun 1:00pmIndianapolisIND -3.5
DEN @ HOU (-1.5)Sun 1:00pmDenverDEN +1.5
JAX (-3.5) @ LVSun 4:05pmLas VegasLV +3.5
NO @ LAR (-14.5)Sun 4:05pmLos AngelesLAR -14.5
KC (-1.5) @ BUFSun 4:25pmBuffaloBUF +1.5
SEA (-3.5) @ WSHSun 8:20pmSeattleSEA -3.5
ARI @ DAL (-2.5)Mon 8:15pmDallasDAL -2.5

Week 8

Game (Fav.)Date/Time (ET)S/U PickATS Pick
MIN @ LAC (-3)Thu 8:15pmLos AngelesLAC -3
SF @ HOU (-1)Sun 1:00pmSan FranciscoSF +1
BUF (-7.5) @ CARSun 1:00pmBuffaloBUF -7.5
NYG @ PHI (-7.5)Sun 1:00pmPhiladelphiaNYG +7.5
CLE @ NE (-7.5)Sun 1:00pmNew EnglandNE -7.5
CHI @ BAL (-6)Sun 1:00pmChicagoCHI +6
NYJ @ CIN (-7)Sun 1:00pmCincinnatiCIN -7
MIA @ ATL (-7.5)Sun 1:00pmAtlantaATL -7.5
TB (-4) @ NOSun 4:05pmTampa BayTB -4
DAL @ DEN (-3.5)Sun 4:25pmDenverDEN -3.5
TEN @ IND (-14.5)Sun 4:25pmIndianapolisIND -14.5
GB (-3) @ PITSun 8:20pmPittsburghPIT +3
WSH @ KC (-13)Mon 8:15pmKansas CityWSH +13

Week 7

Game (Fav.)Date/Time (ET)S/U PickATS Pick
PIT (-5.5) @ CINThu 8:15pmPittsburghCIN +5.5
LAR (-3.5) vs. JAXSun 9:30amLos AngelesLAR -3.5
NO @ CHI (-4.5)Sun 1:00pmChicagoCHI -4.5
MIA @ CLE (-2.5)Sun 1:00pmClevelandCLE -2.5
NE (-7.5) @ TENSun 1:00pmNew EnglandNE -7.5
LV @ KC (-12.5)Sun 1:00pmKansas CityLV +12.5
PHI (-1.5) @ MINSun 1:00pmMinnesotaMIN +1.5
CAR (-1.5) @ NYJSun 1:00pmCarolinaCAR -1.5
NYG @ DEN (-7.5)Sun 4:05pmDenverNYG +7.5
IND @ LAC (-2.5)Sun 4:05pmLos AngelesLAC -2.5
WSH (-1.5) @ DALSun 4:25pmDallasDAL +1.5
GB (-6.5) @ ARISun 4:25pmGreen BayGB -6.5
ATL @ SF (-2.5)Sun 8:20pmSan FranciscoSF -2.5
TB @ DET (-5.5)Mon 7:00pmDetroitTB +5.5
HOU @ SEA (-3.5)Mon 10:00pmSeattleSEA -3.5

Week 6

Game (Fav.)Date/Time (ET)S/U PickATS Pick
PHI (-7.5) @ NYGThu 8:15pmPhiladelphiaNYG +7.5
DEN vs. NYJSun 9:30amDenverDEN -7.5
ARI @ IND (-6.5)Sun 1:00pmIndianapolisIND -6.5
LAC (-4.5) @ MIASun 1:00pmLos AngelesLAC -4.5
NE (-3.5) @ NOSun 1:00pmNew EnglandNE -3.5
CLE @ PIT (-5.5)Sun 1:00pmPittsburghPIT -5.5
DAL (-3.5) @ CARSun 1:00pmDallasDAL -3.5
SEA @ JAX (-1.5)Sun 1:00pmSeattleSEA +1.5
LAR (-7.5) @ BALSun 1:00pmLos AngelesBAL +7.5
TEN @ LV (-4.5)Sun 4:05pmLas VegasLV -4.5
CIN @ GB (-14.5)Sun 4:25pmGreen BayCIN +14.5
SF (-2.5) @ TBSun 4:25pmTampa BayTB +2.5
DET @ KC (-2.5)Sun 8:20pmDetroitDET +2.5
BUF (-3.5) @ ATLMon 7:15pmBuffaloBUF -3.5
CHI @ WSH (-4.5)Mon 8:15pmWashingtonWSH -4.5

Week 5

Game (Fav.)Date/Time (ET)S/U PickATS Pick
SF @ LAR (-7)Thu 8:15pmLos AngelesSF +7
MIN (-3.5) vs. CLESun 9:30amMinnesotaMIN -3.5
HOU (-1) @ BALSun 1:00pmBaltimoreBAL +1
MIA (-1) @ CARSun 1:00pmCarolinaCAR +1
DAL (-2.5) @ NYJSun 1:00pmDallasDAL -2.5
NYG @ NO (-2)Sun 1:00pmNew YorkNYG +2
LV @ IND (-7)Sun 1:00pmIndianapolisIND -7
DEN @ PHI (-3.5)Sun 1:00pmPhiladelphiaPHI -3.5
TB @ SEA (-3.5)Sun 4:05pmSeattleSEA -3.5
TEN @ ARI (-7.5)Sun 4:05pmArizonaARI -7.5
WSH @ LAC (-3)Sun 4:25pmLos AngelesLAC -3
DET (-10.5) @ CINSun 4:25pmDetroitDET -10.5
NE @ BUF (-8)Sun 8:20pmBuffaloBUF -8
KC (-3.5) @ JAXMon 8:15pmKansas CityKC -3.5

Week 4

Game (Fav.)Date/Time (ET)S/U PickATS Pick
SEA (-1.5) @ ARIThu 8:15pmArizonaARI +1.5
MIN (-2.5) vs. PITSun 9:30amPittsburghPIT +2.5
WSH (-1) @ ATLSun 1:00pmWashingtonWSH -1
CLE @ DET (-10.5)Sun 1:00pmDetroitDET -10.5
LAC (-6.5) @ NYGSun 1:00pmLos AngelesLAC -6.5
TEN @ HOU (-7)Sun 1:00pmHoustonTEN +7
CAR @ NE (-5.5)Sun 1:00pmNew EnglandCAR +5.5
NO @ BUF (-15.5)Sun 1:00pmBuffaloBUF -15.5
PHI (-3.5) @ TBSun 1:00pmTampa BayTB +3.5
JAX @ SF (-3)Sun 4:05pmSan FranciscoSF -3
IND @ LAR (-3.5)Sun 4:05pmLos AngelesLAR -3.5
BAL (-2.5) @ KCSun 4:25pmBaltimoreBAL -2.5
CHI @ LV (-1)Sun 4:25pmChicagoCHI +1
GB (-7) @ DALSun 8:20pmGreen BayGB -7
NYJ @ MIA (-3)Mon 7:15pmMiamiMIA -3
CIN @ DEN (-7.5)Mon 8:15pmDenverDEN -7.5

Week 3

Game (Fav.)Date/Time (ET)S/U PickATS Pick
MIA @ BUF (-13)Thu 8:15pmBuffaloBUF -13
LAR @ PHI (-3)Sun 1:00pmPhiladelphiaPHI -3
LV @ WSH (-3.5)Sun 1:00pmWashingtonWSH -3.5
HOU @ JAX (-1.5)Sun 1:00pmJacksonvilleJAX -1.5
PIT (-1) @ NESun 1:00pmPittsburghPIT -1
IND (-4) @ TENSun 1:00pmIndianapolisIND -4
GB (-7.5) @ CLESun 1:00pmGreen BayGB -7.5
ATL (-5.5) @ CARSun 1:00pmAtlantaATL -5.5
CIN @ MIN (-3)Sun 1:00pmMinnesotaMIN -3
NYJ @ TB (-7)Sun 1:00pmTampa BayTB -7
DEN @ LAC (-3)Sun 4:05pmLos AngelesLAC -3
NO @ SEA (-7.5)Sun 4:05pmSeattleSEA-7.5
DAL (-1) @ CHISun 4:25pmChicagoCHI +1
ARI @ SF (-2.5)Sun 4:25pmSan FranciscoSF -2.5
KC (-6) @ NYGSun 8:20pmKansas CityKC -6
DET @ BAL (-5)Mon 8:15pmBaltimoreDET +5

Week 2

Game (Fav.)Date/Time (ET)S/U PickATS Pick
WSH @ GB (-3.5)Thu 8:15pmGreen BayGB -3.5
JAX @ CIN (-3.5)Sun 1:00pmCincinnatiCIN -3.5
NYG @ DAL (-5.5)Sun 1:00pmDallasDAL -5.5
CHI @ DET (-5.5)Sun 1:00pmDetroitCHI +5.5
LAR (-5.5) @ TENSun 1:00pmLos AngelesTEN +5.5
NE @ MIA (-1.5)Sun 1:00pmMiamiMIA -1.5
SF (-4.5) @ NOSun 1:00pmSan FranciscoSF -4.5
BUF (-6.5) @ NYJSun 1:00pmBuffaloNYJ +6.5
SEA @ PIT (-2.5)Sun 1:00pmPittsburghPIT -2.5
CLE @ BAL (-11.5)Sun 1:00pmBaltimoreBAL -11.5
DEN (-1.5) @ INDSun 4:05pmDenverDEN -1.5
CAR @ ARI (-6.5)Sun 4:05pmArizonaARI -6.5
PHI (1.5) @ KCSun 4:25pmKansas CityKC +1.5
ATL @ MIN (-3.5)Sun 8:20pmMinnesotaMIN -3.5
TB @ HOU (-2.5)Mon 7:00pmHoustonHOU -2.5
LAC (-3.5) @ LVMon 10:00pmLos AngelesLAC -3.5

Week 1

Game (Fav.)Date/Time (ET)S/U PickATS Pick
DAL @ PHI (-8.5)Thu 8:20pmPhiladelphiaPHI -8.5
KC (-3.5) vs. LACFri 8pmKansas CityKC -3.5
NYG @ WSH (-6.5)Sun 1pmWashingtonNYG +6.5
TB (-2.5) @ ATLSun 1pmAtlantaATL +2.5
CIN (-4.5) @ CLESun 1pmCincinnatiCLE +4.5
MIA @ IND (-1.5)Sun 1pmMiamiMIA +1.5
LV @ NE (-2.5)Sun 1pmNew EnglandNE -2.5
ARI (-6.5) @ NOSun 1pmArizonaNO +6.5
PIT (-2.5) @ NYJSun 1pmPittsburghPIT -2.5
CAR @ JAX (-3.5)Sun 1pmJacksonvilleJAX -3.5
TEN @ DEN (-7.5)Sun 4:05pmDenverDEN -7.5
SF (-2.5) @ SEASun 4:05pmSeattleSEA +2.5
DET @ GB (-2.5)Sun 4:25pmGreen BayGB -2.5
HOU @ LAR (-2.5)Sun 4:25pmLos AngelesLAR -2.5
BAL @ BUF (-1.5)Sun 8:20pmBuffaloBUF -1.5
MIN (-1.5) @ CHIMon 8:15pmChicagoCHI +1.5

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